Leishmania tarentolae cells in brain-heart infusion medium were partially synchronized in terms of DNA synthesis and cell division by a 10 hour period of inhibition in 200 μg/ml
We raised a specific antiserum against the recombinant M 2 subunit protein of ribonucleotide reductase of Leishmania mexicana amazonensis in rabbit
SYNOPSIS Leishmania tarentolae cells in brain-heart infusion medium were partially synchronized in terms of DNA synthesis and cell division by a 10 hour period of inhibition in 200 μg/ml hydroxyurea at 27 C
Leishmania mexicana is a protozoan parasite that causes a disease in humans with frequent relapses after treatment
gondii, and T
Parasitol Res, 85(3):188-193, 01 Mar 1999 Cited by: 3 articles | PMID: 9951961 A useful method to synchronize procyclic promastigote forms of Leishmania amazonensis using hydroxyurea (HU) and the analysis of its DNA content profile is described, which provides an effective method for arresting more than 80% of cells at the G1/S phase transition
Hydroxyurea (HU) is mostly referred to as an inhibitor of ribonucleotide reductase (RNR) and as the agent that is commonly used to arrest cells in the S-phase of the cycle by inducing replication stress
We raised a specific antiserum against the recombinant M 2 subunit protein of ribonucleotide reductase of Leishmania mexicana amazonensis in rabbit
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For this reason, there is an urgent need for more effective antileishmanial drugs
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Hydroxyurea, an | Hydroxyurea, Leishmania mexicana and Leishmania | ResearchGate, the professional network for scientists
For this reason, there is an urgent need for more effective antileishmanial drugs
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