Verapamil is both a substrate and an inhibitor of CYP3A4, which is inhibited by
Verapamil also increases the supply of blood and oxygen to the heart and slows
The mechanism of action of verapamil is as a Calcium Channel Antagonist, and
Die Zügelung des Myocardstoffwechsels durch Verapamil
Journal List
Verapamil • The non-dihydropyridine calcium channel antagonists, verapamil and diltiazem, exhibit antiarrhythmic effects predominately at the AV-node via blocking of slow Verapamil and cinnarizine are other meds that are off-label for migraine prevention
MeSH terms Verapamil is a medication sometimes prescribed to prevent migraine headaches
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Verapamil’s neuroprotective mechanism(s) of action remain to be elucidated
The concurrent use of verapamil or diltiazem will increase ivabradine exposure, and these drugs may contribute to lowering of the heart rate
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Mechanism of Action