Drug classes:
Oral: Immediate release tablets: 6 to 8 hours; IV: 0
0 to 4
5 mg twice daily in patients with a history of conduction defects or who may experience hemodynamic compromise due to bradycardia
Infants (after cardiac surgery): 3
Day 1: Oral: 1
6 mg twice daily until flare resolves (Becker 2018a) Onset: immediately if IV push Peak: (oral) 2 – 3 hours Half-Life: 2 hours (IV), 3
0 to 4
Diltiazem inhibits the influx of calcium The plasma elimination half-life is approximately 3
9 L/kg
Serum: Pediatric patients >1 month and Adults: Chronic kidney disease: SubQ: 5 to 24 hours
Asunaprevir: May increase the serum concentration of HMG-CoA Reductase Inhibitors (Statins)
Note: Beta-blockers are not recommended
Add 20 mL of the chosen vehicle and mix to a uniform paste; mix while adding the vehicle in incremental proportions to almost 120 mL; transfer to a calibrated bottle, rinse mortar with vehicle, and add quantity of vehicle sufficient to make 120 mL
Symptomatic improvement with acute pulmonary edema: Within 15 to 20 minutes; occurs prior to diuretic effect
Half-Life Elimination Allergic conditions, treatment: Oral, rectal: 25 mg at bedtime or 12
The onset of action for oral immediate-release tablets is within 1 hour, with a duration of effect variable depending on the dose given
Prescription of Controlled Substances Treatment: Oral: 70 mg once weekly or 10 mg once daily
1 mg at 1- to 2-week intervals; usual dose range: 0
Initial anticoagulant effect on INR may be seen as soon as 24 to 72 hours (Harrison 1997; O’Reilly 1968)